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1996-02-27
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Document 0577
DOCN M9630577
TI Effect of administration of serum thymic factor (FTS) in calves and
rabbits infected with bovine immunodeficiency-like virus.
DT 9603
AU Hirai N; Furuyama H; Awaya A; Onuma M; Department of Epizootiology,
Faculty of Veterinary Medicine,; Hokkaido University, Japan.
SO J Vet Med Sci. 1995 Apr;57(2):307-10. Unique Identifier : AIDSLINE
MED/96114695
AB The effect of serum thymic factor (FTS) administration in bovine
immunodeficiency-like virus (BIV)-infected calves and rabbits was
examined. We previously found that some of the macrophage functions were
depressed and humoral immune responses against foreign proteins were
delayed in BIV-infected calves compared to uninfected calves. After FTS
administration, however, no delay of antibody responses against foreign
proteins was observed in BIV-infected calves. Though the
chemiluminescence (CL) responses of macrophages in BIV-infected calves
were significantly depressed (p < 0.05), FTS administration resulted in
the recovery of the CL responses in the BIV-infected calves comparable
to those in the control calves. Antibody responses against foreign
proteins in BIV-infected rabbits were significantly depressed (p <
0.025) as compared with those in uninfected rabbits, though the
depression became no significant after FTS administration.
DE Animal Antibody Formation Blood Proteins/IMMUNOLOGY Cattle
Chemiluminescence Erythrocytes/IMMUNOLOGY *Immunodeficiency Virus,
Bovine Lentivirus Infections/*IMMUNOLOGY/THERAPY
Macrophages/*IMMUNOLOGY Mice Rabbits Sheep Thymic Factor,
Circulating/*PHARMACOLOGY Time Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).